WINSTROL 10

DESCRIPTION
Stanozolol 10 is an oral androgen derived from dihydrotestosterone. Stanozolol 10 acts on
androgen receptors to promote anabolism through increased nitrogen retention and protein
synthesis in muscle tissue. Stanozolol 10 is a strong anabolic substance with androgenic
action. Stanozolol does not convert to estrogen and therefore does not produce typical
estrogen mediated side effects such as water retention. Stanozolol has a large oral
bioavailability, due to a C17 a-alkylation which allows the hormone to survive first pass liver
metabolism. Stanozolol reduces SHBG increasing free testosterone levels.

INDICATIONS
Hereditary Angioedema: for prophylactic use to decrease frequency and severity of attacks
of angioedema. Muscle Anabolism: for adjunctive therapy in patients for weight gain
following severe muscular atrophy associated with extensive surgery, chronic infections,
long term hospitali- zation, or severe trauma. Corticosteroid Atrophy: to reduce muscle
wasting during prolonged corticosteroid use.

ADVERSE REACTIONS
Male: Gynecomastia, excessive frequency and duration of penile erections, oligospermia.
Skin and Appendages: Hirsutism, male pattern baldness and acne, gynecomastia.
Fluid/electrolyte Disturbances: Retention of sodium, chloride, water, potassium, calcium, and inorganic phosphates.
Gastrointestinal: Nausea, cholestatic jaundice, alterations in liver function tests; rarely, hepatocellular neoplasms, peliosis hepatis, hepatic adenomas, and
cholestatic hepatitis.
Hematologic: Suppression of clotting factors II, V, VII, & X: bleeding in patients on anti- coagulant therapy.
Nervous System: Increased or decreased libido, headache, anxiety, depression, and generalized paresthesia.
Other: Serum lipid changes, hypercalcaemia, hypertension, oedema, priapism, and potentiation of sleep apnea.

CONTRAINDICATIONS
Not for use in female patients due to risk of virilization and fetal harm. Male patients with
known or suspected carcinoma of the breast, prostate, or testis. Patients with
hypercalcaemia as anabolic steroids may stimulate osteolytic bone resorption. Patients with
cardiovascular disorders, renal or hepatic impairment, epilepsy, migraines, or diabetes
mellitus. Nephrosis or the nephrotic phase of nephritis.

DOSAGE AND ADMINISTRATION
Muscle anabolism: 10 30mg taken orally each day in divided doses for a duration of 4 -6
weeks. Hereditary angioedema: 2 – 6 mg taken orally each day in divided doses initially &
reduced by physician thereafter. The use of anabolic steroids is associated with serious
adverse reactions. Such reactions are often dose dependent. Physicians are urged to treat
patients with the lowest possible effective dose.

PRESENTATION
Stanozolol 10 mg uncoated tablets: 100 tablets in blister

STORAGE
Store in a cool dry place between 15 – 25°C, Protect from beau light.